cognition

Trajectory of Neurocognitive Functioning in Children Treated for Acute Lymphoblastic Leukemia (ALL): Dana-Farber Cancer Institute ALL Consortium Study 16-001

Authors: Alexandra Thrope, Sameera Ramjan, Charlie White, Audrey Mauguen, Lewis B Silverman, Jennifer J G Welch, Justine Kahn, Kara M Kelly, Thai-Hoa Tran, Bruno Michon, Lisa Gennarini, Yongkyu Park, Peter D Cole, Stephen A Sands

Journal: Pediatric Blood & Cancer

Year Published: 2026

Background: Children treated for acute lymphoblastic leukemia (ALL) are at risk of neurocognitive deficits in attention-concentration, working memory, executive function, and psychomotor speed. Objectives: This study evaluated longitudinal trajectories and medical/demographic associations with neurocognitive outcomes during […]

Evaluating Physical Frailty as a Marker of Cognitive Health in Older Adults without Dementia

Authors: Youngmin Cho, Jing Huang, Sofia Liu, Nada Lukkahatai, Jessica Gill, Junxin Li

Journal: Journal of Geriatric Psychiatry and Neurology

Year Published: 2026

Physical frailty is associated with adverse health outcomes in older adults, including cognitive decline; however, the underlying biological and pathophysiological mechanisms linking frailty to neuropathological biomarkers remain underexplored, particularly in older adults without dementia. This study […]

The proportion of plant-based food consumption during midlife and cognitive health in later life in Australian women: data from the Women’s Healthy Ageing Project (WHAP)

Authors: Phuong Le, Cassandra Szoeke, Kaitlin Day, Russell Conduit, Sharayah Carter, Catherine Itsiopoulos

Journal: European Journal of Nutrition

Year Published: 2025

Purpose: Plant-based food (PBF) is well-known for its benefits for physical health; however, its impacts on brain health are less well understood, especially in ageing women. This study aimed to examine the association between different proportions […]

Cognitive Performance in Late Midlife as a Predictor of Frailty from Late Midlife into Old Age: A Longitudinal Birth Cohort Study

Authors: Anna Tirkkonen, Markus J Haapanen, Hanna Pajulammi, Jenni Niku, Juulia Jylhävä, Tuija M Mikkola, Eero Kajantie, Johan G Eriksson, Mikaela B von Bonsdorff

Journal: Gerontology

Year Published: 2025

Introduction: Cognitive decline is cross-sectionally associated with frailty in older adults. However, the longitudinal associations between cognitive performance in late midlife and subsequent frailty are less well understood. Methods: Participants of the Helsinki Birth Cohort Study […]

Cognitive function at the time of focal epilepsy diagnosis is not associated with treatment resistance

Authors: Jacob Pellinen, Stefan Sillau, Chris Morrison, Paul Maruff, Terence J O'Brien, Patricia Penovich, Jacqueline French, Kelly G Knupp, Sarah Barnard, Manisha Holmes, Manu Hegde, Andres M Kanner, Kimford J Meador

Journal: Epilepsy & Behavior

Year Published: 2025

Objective: Seizures can impact cognition both acutely and chronically. However, among those without significant comorbidities and broadly average cognition at epilepsy onset, the relationship between cognitive function at the time of diagnosis and long-term seizure control […]

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