Trajectory of Neurocognitive Functioning in Children Treated for Acute Lymphoblastic Leukemia (ALL): Dana-Farber Cancer Institute ALL Consortium Study 16-001
Background: Children treated for acute lymphoblastic leukemia (ALL) are at risk of neurocognitive deficits in attention-concentration, working memory, executive function, and psychomotor speed. Objectives: This study evaluated longitudinal trajectories and medical/demographic associations with neurocognitive outcomes during […]
Evaluating Physical Frailty as a Marker of Cognitive Health in Older Adults without Dementia
Physical frailty is associated with adverse health outcomes in older adults, including cognitive decline; however, the underlying biological and pathophysiological mechanisms linking frailty to neuropathological biomarkers remain underexplored, particularly in older adults without dementia. This study […]
The proportion of plant-based food consumption during midlife and cognitive health in later life in Australian women: data from the Women’s Healthy Ageing Project (WHAP)
Purpose: Plant-based food (PBF) is well-known for its benefits for physical health; however, its impacts on brain health are less well understood, especially in ageing women. This study aimed to examine the association between different proportions […]
Cognitive Performance in Late Midlife as a Predictor of Frailty from Late Midlife into Old Age: A Longitudinal Birth Cohort Study
Introduction: Cognitive decline is cross-sectionally associated with frailty in older adults. However, the longitudinal associations between cognitive performance in late midlife and subsequent frailty are less well understood. Methods: Participants of the Helsinki Birth Cohort Study […]
Cognitive function at the time of focal epilepsy diagnosis is not associated with treatment resistance
Objective: Seizures can impact cognition both acutely and chronically. However, among those without significant comorbidities and broadly average cognition at epilepsy onset, the relationship between cognitive function at the time of diagnosis and long-term seizure control […]