Lower dorsal putamen D2/3 receptor availability and amphetamine-induced dopamine release are related to poorer cognitive function in recently abstinent people who smoke and healthy controls

Authors: Frances Cheung, Katina C Calakos, Ralitza Gueorguieva, Ansel T Hillmer, Kelly P Cosgrove, Yasmin Zakiniaeiz

Journal: Nicotine & Tobacco Research

Year Published: 2024

Introduction: In the dopamine system, the mesolimbic pathway, including the dorsal striatum, underlies the reinforcing properties of tobacco smoking, and the mesocortical pathway, including the dorsolateral prefrontal cortex (dlPFC), is critical for cognitive functioning. Dysregulated dopamine […]

Cognitive Functioning and Psychosocial Outcomes in Adults with Complex Congenital Heart Disease: A Cross-sectional Pilot Study

Authors: Charlotte E Verrall, Derek L Tran, Nadine A Kasparian, Tracey Williams, Vincent Oxenham, Julian Ayer, David S Celermajer, Rachael L Cordina

Journal: Pediatric Cardiology

Year Published: 2024

Adults with complex congenital heart disease (CHD) are at risk for cognitive dysfunction. However, associations between cognitive dysfunction and psychosocial outcomes are poorly defined. Between June and November 2022, we prospectively recruited 39 adults with complex […]

Higher orexin-A levels are associated with treatment response to clozapine in patients with schizophrenia: A cross-sectional study

Authors: Po-Yu Chen, Chih-Chiang Chiu, Chin-Kuo Chang, Mong-Liang Lu, Cho-Yin Huang, Chun-Hsin Chen, Ming-Chyi Huang

Journal: Journal of Psychopharmacology

Year Published: 2024

Background: Clozapine is the primary antipsychotic (APD) for treatment-resistant schizophrenia (TRS). However, only 40% of patients with TRS respond to clozapine, constituting a subgroup of clozapine-resistant patients. Recently, the neuropeptide orexin-A was shown to be involved […]

Social determinants of health and cognitive function: A cross-sectional study among men without dementia

Authors: Kayla B Corney, Julie A Pasco, Amanda L Stuart, Bianca E Kavanagh, Mohammadreza Mohebbi, Sophia X Sui, Lana J Williams

Journal: Brain and Behavior

Year Published: 2023

Background Certain age-related and medical factors have been associated with cognitive dysfunction; however, less is known regarding social determinants of health. The current study aimed to investigate associations between social determinants of health and cognitive function […]

Post-traumatic stress disorder symptom remission and cognition in a large cohort of civilian women

Authors: Jiaxuan Liu, Andrea L Roberts, Rebecca B Lawn, Shaili C Jha, Laura Sampson, Jennifer A Sumner, Jae H Kang, Eric B Rimm, Francine Grodstein, Liming Liang, Sebastien Haneuse, Laura D Kubzansky, Karestan C Koenen, Lori B Chibnik

Journal: Psychological Medicine

Year Published: 2023

Background Post-traumatic stress disorder (PTSD) is associated with cognitive impairments. It is unclear whether problems persist after PTSD symptoms remit. Methods Data came from 12 270 trauma-exposed women in the Nurses’ Health Study II. Trauma and […]

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