clinical trials

Cognitive Outcomes after DEXmedetomidine sedation in cardiac surgery: CODEX randomised controlled trial protocol

Authors: Stephen Choi, Angela Jerath, Philip Jones, Sinziana Avramescu, George Djaiani, Summer Syed, Tarit Saha, Lilia Kaustov, Alex Kiss, Frédérick D'Aragon, Peter Hedlin, Raja Rajamohan, Etienne J Couture, Amara Singh, Josiane Cs Mapplebeck, Sophia Wong, Beverley Anne Orser

Journal: BMJ Open

Year Published: 2021

Introduction Older patients undergoing cardiac surgery carry the highest risk for developing major postoperative neurocognitive disorder (postoperative NCD or P-NCD) with up to 25% incidence 3 months after surgery. P-NCD is associated with significant morbidity, mortality, […]

Preliminary exploration of a computerized cognitive battery and comparison with traditional testing in patients with high-grade glioma

Authors: Jane H Cerhan, Chip Caine, S Keith Anderson, Derek R Johnson, Daniel H Lachance, Elizabeth Yan, Paul D Brown

Journal: Neuro-Oncology Practice

Year Published: 2019

Background: Cognitive function is an important outcome measure in many brain tumor clinical trials, and investigators are interested in employing the most efficient methods of cognitive assessment for this purpose. Computerized testing can be appealing because […]

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