cerebrovascular disease

A 24-week Study to Evaluate the Effect of Rilapladib on Cognition and Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease

Authors: Andrew Lockhart, Arseniy Lavrov, Carly Barnett, Gareth Maher-Edwards, Jeni De'Ath

Journal: Alzheimer's & Dementia

Background: The lipoprotein-associated phospholipase A2 inhibitor (Lp-PLA2), rilapladib (SB659032), is being evaluated as a potential treatment to slow the progression of Alzheimer’s disease (AD). Methods: One hundred twenty-four subjects with possible mild AD and with neuroimaging […]

Cutting a long story short: reaction times in acute stroke are associated with longer term cognitive outcomes.

Authors: Bernhardt J, Brodtmann A, Cumming TB, Darby D

Journal: Journal of the Neurological Sciences

BACKGROUND: The viability and usefulness of cognitive assessment in acute stroke have been questioned, with practical challenges arising from the focal nature of neurological deficits as well as heterogeneity in arousal state. We aimed to test […]

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