The National Institute on Aging and the Alzheimer’s Association Research Framework for Alzheimer’s disease: Perspectives from the Research Roundtable.

December 10, 2019

Authors: Bain LJ, Canniere MZ, Carrillo MC, Haeberlein SB, Hendrix JA, Jack CR Jr, Kerchner G, Knopman DS, Kolb H, Margolin R, Maruff P, Mattsson N, Miller DS, Montine TJ, Murray ME, Nelson PT, Petersen RC, Resnick SM, Romano G, Sano M, Schneider JA, Siemers E, Sultzer DL, Tome MB, Tong G, van Harten AC, Vemuri P, Wolk DA

Journal: Alzheimer's and Dementia

DOI: 10.1016/j.jalz.2018.03.002

Year Published: 2018

The Alzheimer’s Association’s Research Roundtable met in November 2017 to explore the new National Institute on Aging and the Alzheimer’s Association Research Framework for Alzheimer’s disease. The meeting allowed experts in the field from academia, industry, and government to provide perspectives on the new National Institute on Aging and the Alzheimer’s Association Research Framework. This review will summarize the “A, T, N System” (Amyloid, Tau, and Neurodegeneration) using biomarkers and how this may be applied to clinical research and drug development. In addition, challenges and barriers to the potential adoption of this new framework will be discussed. Finally, future directions for research will be proposed.

Back to Publications