Reliability of repeated cognitive assessment of dementia using a brief computerized battery.

November 5, 2014

Authors: Albin R, Barbas N, Darby D, Frey K, Giordani B, Hammers D, Heidebrink J, Persad C, Ryan K, Spurgeon E

Journal: American Journal of Alzheimer's Disease and Other Dementias

DOI: 10.1177/1533317511411907

Year Published: 2011

The aim of this study was to evaluate the short-term stability and reliability of a brief computerized cognitive battery in established dementia types.

Patients were administered the computerized battery twice with administrations approximately 2 hours apart, with intervening conventional neuropsychological tests. Patients were classified clinically, via consensus conference, as healthy controls (n = 23), mild cognitive impairment (n = 20), Alzheimer’s disease (n = 52), dementia with Lewy Bodies ([DLB], n = 10), or frontotemporal dementia (n = 9).

Minimal practice effects were evident across Cog-State test administrations. Small magnitude improvements were seen across all groups on a working memory task, and healthy controls showed a mild practice effect on the accuracy of associative learning.

In established dementia, administration of the CogState tasks appears sensitive to cognitive impairment in dementia. Repeat administration also provided acceptable stability and test-retest reliability with minimal practice effects at short test-retest intervals despite intervening cognitive challenges.

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