Optimize Clinical Outcomes for Greater Signal Detection

Cogstate’s team of scientific and operational experts can help advise your team on efficient and effective study conduct in pediatric and rare disease trials. Working with our team gives you access to robust data quality programs and reliable computerized assessments.

Implement Robust Data Quality Programs In rare disease trials, often the assessments are complex and eligible participants limited. With numerous and geographically dispersed trial sites, inter-rater variability can compromise data quality. Not to mention, many sites are highly specialized, and raters are participating in several similar trials simultaneously. As such, high-quality rater training and data monitoring programs are essential. Cogstate supports all aspects of data quality programs with proven methodologies and leading technologies that drive endpoint reliability.

Leverage Sensitive and Reliable Computerized Batteries Cogstate’s computerized batteries of highly sensitive tests provide rapid and reliable measurement of distinct cognitive domains affected by rare diseases. The tests are grouped into customizable batteries for a complete and nuanced picture of a subject’s cognitive state. Cogstate tests are culture- and education-neutral and designed for repeated administration with minimal practice or learning effects, making them ideal for use in global clinical trials. Cogstate tests are available in pediatric versions.

Rare Disease and Pediatric Center for Excellence

With the vital need for effective cognitive measurement in rare disease and pediatric clinical trials, Cogstate has established a Rare Disease and Pediatric Center of Excellence. The Center provides industry-leading clinical and scientific expertise focused on the selection, adaptation, optimization, validation and administration of cognitive and behavioral measures in clinical studies in rare diseases and pediatrics.

Pam Ventola, PhD
VP Science, Associate Professor at the Yale Child Study Center

Dr. Ventola leads Cogstate’s Rare Disease and Pediatric Center for Excellence, providing Cogstate customers with strategic oversight and expert guidance throughout all stages of their study planning and execution – from endpoint selection, rater training and strategic monitoring to final statistical analysis. As a licensed clinical psychologist, Dr. Ventola’s primary clinical expertise is in pediatric neuropsychology and specifically developmental and genetic disorders. Dr. Ventola received her Doctor of Philosophy in Clinical Psychology from University of Connecticut and completed her clinical training and Postdoctoral Fellowship at the Yale University School of Medicine, Child Study Center.