Improve Strategic Study Design
Choosing appropriate endpoints and designing and powering trials are just two examples of the many make-or-break decisions in the planning phase that impact future trial results. Cogstate has the expertise and extensive data sets to advise your team on vital study considerations, help you answer key drug development questions, and reduce risk and uncertainty.
|Leverage Insights from Key Landmark Studies
Cogstate is at the forefront of Alzheimer’s research via participation in several key longitudinal public private partnership (PPP) studies such as secondary prevention trials including A4 and DIAN, as well as registries and natural history studies including AIBL, ADNI, BHR, and the APT Webstudy, many of which offer open data sharing to advance collaborative research.
|Gain Study Design Guidance from Cognitive Science Experts
Utilizing open data sets made available through our involvement in PPPs, Cogstate scientists are able to advise study teams on endpoint selection, powering decisions, and interpretation of study results supportive of product efficacy, safety, and differentiating claims.
|Develop Go/No-Go Decision-Making Frameworks
Optimize Clinical Outcome Assessment for Enhanced Signal Detection
Cogstate’s team of scientific and operational experts deliver innovative technology, proven operational delivery models and leading scientific support for both digital and conventional clinical outcome assessments in AD trials.
|Leverage Sensitive and Reliable Computerized Batteries
Cogstate’s computerized batteries of highly sensitive tests provide rapid and reliable measurement of distinct cognitive domains affected by mild cognitive impairment, pre-clinical AD and mild-to-moderate AD. They are grouped into customizable batteries for a complete and nuanced picture of a subject’s cognitive state. Cogstate tests are culture- and education-neutral and designed for repeated administration with minimal practice or learning effects, making them ideal for use in global clinical trials.
|Implement Robust Data Quality Programs for Conventional Assessments
Subjective assessments create the potential for variability in administration and scoring that may compromise the integrity of a study. Cogstate supports all aspects of data quality programs—rater training and certification, subject eligibility review, eCOA deployment, central monitoring—with proven methodologies and leading technologies that drive endpoint reliability.