Research Shows Exercise Has Positive Effects on Cognition in Veterans with Depression and BDNF Val66Met Mutation
A recent study, published in the American Journal of Geriatric Psychiatry, compared the cognitive health of veterans with and without depression alongside their reported level of physical activity and the presence of a variation to a genetic protein known to improve brain plasticity. The study data was gathered from 1,386 U.S. military veterans over the age of 50; each took a web-based survey that included the Cogstate Brief Battery.
Study Links Repetitive Head Impacts and Traumatic Brain Injury with Depression and Cognitive Dysfunction
New research has reinforced the direct relationship between repetitive head impacts, traumatic brain injury and neurological dysfunction later in life. While a logical link exists, this most recent study provides insight into not only cognitive challenges, like working memory, processing speed, learning and reaction time, but also the onset of depression as a result of experience with contact sports, physical abuse or military service.
A4 Study Baseline Data Show C3 Computerized Battery has Potential as Proxy for Paper and Pencil Measures in AD Prevention Trials
Results from the A4 study baseline assessments have identified that the Computerized Cognitive Composite (C3) battery has potential to serve as a proxy for paper and pencil measures in AD prevention trials. Cogstate’s CSO sat down with Dr. Kate Papp, the lead author of a recent publication showcasing C3 data.
AHRQ Systematic Review Classifies Cogstate Cognitive Tests as Highly Sensitive and Specific in Distinguishing Alzheimer’s Disease
A recent review of the cognitive tests available for identifying impairment related to Alzheimer’s disease and its very early stages ranked both the Cogstate Brief Battery (CBB) and the Cogstate International Shopping List Test in the highest bracket for sensitivity and specificity at distinguishing CATD from normal cognition.
Study Shows Scopolamine Challenge Test May be a Viable Screening Tool for Aβ-related Cognitive Decline in Preclinical Alzheimer’s Disease
While PET scanning will remain important, the scopolamine challenge test (SCT) may offer another method for understanding early AD related changes in people at risk for the disease.
Cogstate Computerized Cognitive Testing Receives High Patient Ratings in Diverse Primary Care Settings
Early detection of cognitive impairment in adults is important in planning care for Alzheimer’s Disease. Computerized assessment of cognition has the potential to be leveraged in mainstream primary care settings to efficiently and accurately test millions. Read the research results from SUNY.
Soccer Players Who Carry APOE ε4 Variant at Greater Risk from Frequent Heading
JAMA Neurology published data from a recent study showing soccer players who head the ball more frequently experience episodic memory loss, as demonstrated by lower scores on the Cogstate International Shopping List Delayed Recall (ISRL) test.
Cogstate Celebrates 20 Years of Advancing Brain Health Assessment
Martyn Myer AO, Cogstate Chairman, reflects on the history of the company and neuroscience research in Australia.
Study Used Cogstate ISLT to Examine the Impact of Cannabis Use on Learning and Memory Function in Young Adults
Chosen by the researchers for its reliability across language translations and its validity for measuring verbal memory, the Cogstate ISLT assesses immediate and delayed recall of a 12-item list. Read how the ISLT was used by a multi-university team to study the impact of cannabis.
Review of Recent FDA Draft Guidance for Rare Disease Clinical Trials
Dr. Pam Ventola reviews two recent FDA draft guidances for rare disease drug development in this video. Learn about the need for indication-specific outcomes, as well as how to get the most from natural history studies to determine acceptability/feasibility of endpoints and inform future trial designs.
