April 2016

The latest from Cogstate, leaders in optimizing the measurement of cognition

Study Provides New Insight Into Relationship Of Beta Amyloid And APOE4 To Cognitive Decline

April 29, 2016

In the continuing search for the underlying causes of Alzheimer’s disease, two biomarkers consistently demonstrate their significance; the levels of beta amyloid (Aβ) in the brain and the presence of the Apolipoprotein E (APOE) ε4 allele genotype. Previous studies have shown that in cognitively normal older adults, the combination of high levels of Aβ with […]

Lithium Treatment For Bipolar Disorder Shown To Also Improve Verbal Fluency

April 19, 2016

During the dramatic mood swings of bipolar disorder (BP), between depression and euphoric mania, patients often experience cognitive impairment particularly in working memory, verbal fluency and visual memory. A mix of a mood stabilizer (lithium) and an antipsychotic (quetiapine) is often prescribed to treat BP symptoms. However, there are mixed reports on the effect of […]

Dementia With Lewy Bodies Predicted By Autonomic Testing in Major Depressive Disorder

April 1, 2016

As the third leading type of dementia, behind only Alzheimer’s disease and vascular dementia, dementia with Lewy bodies (DLB) is often linked with symptoms similar to Parkinson’s disease. Present in several other brain disorders, Lewy bodies are abnormal aggregates of protein, primarily alpha-synuclein. Detecting Lewy bodies early before dementia-related symptoms emerge is important to the […]