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• Data Flow & Quality
  • Dataflow
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• Our Process
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• Our Test Batteries
  • Early Phase Battery
  • Schizophrenia Battery
  • ADHD Battery
• Our Tasks
  • Detection Task
  • Identification Task
  • One Card Learning Task
  • One Word Learning Task
  • One Back Task
  • Two Back Task
  • Monitoring Task
  • International Shopping List Task
  • International Shopping List Task - Delayed Recall
  • Chase Test
  • Groton Maze Learning Test
  • Groton Maze Learning Test - Delayed Recall
  • Groton Maze Learning Test - Reverse Delayed Recall
  • Social-Emotional Cognition Task
  • Set-Shifting Task
  • Continuous Paired Associate Learning Task
  • Continuous Paired Associate Learning Task: Delayed Recall
• Introduction
  • About Cognitive Testing
  • Why CogState?
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CogState ClinicalTrials comprises a customizable range of computerized cognitive tasks able to measure baseline and change in all cognitive domains. Specialized tasks can assess attention, memory, executive function, as well as language and social-emotional cognition if required. Our batteries of tasks are used in research and commercial trials to determine the effect on cognition of drugs, devices, nutraceuticals and other interventions in many different conditions, diseases and disorders, and also in healthy volunteers. They are also used in large-scale sports medicine and screening programs where conventional testing is not feasible.

Validity, Reliability, Sensitivity

• The CogState testing method has been validated in international peer-reviewed journals. It targets a wide range of cognitive domains, including simple reaction time, attention, executive function and social-emotional cognition.
• Our tests are designed to maximize the signal and minimize the noise from cognitive recordings taken in clinical trials. They have a proven ability to detect both improvement and decline in cognition.
• Excellent stability allows for the detection of subtle drug effects, meaning that any change in cognition - no matter how small - will be detected.
• Minimal learning effects ensure that subjects can be retested as many times and as often as needed, even multiple times in short periods - as may occur, for example, during early-phase clinical trials.

Rapidity

• Our tests are the fastest computerized tests in the world. A brief battery can be completed in as little as 7 minutes without loss of sensitivity, and a more extensive battery in only 25 minutes, ensuring ease of integration into a busy clinical trial schedule.
• When dealing with difficult patient groups such as those with Schizophrenia and ADHD, the ability to collect the optimum amount of data in the shortest possible time is a significant advantage.

Experience

• Our tests have been used extensively by leading FDA-regulated pharmaceutical companies in phase I to phase IV trials with both healthy volunteers and patient groups.
• We are experts in developing tests that allow for non-expert administration using standard equipment, making it simpler and more cost effective to integrate cognitive testing into any clinical trial.

Quality Data, Delivered Faster

• FDA 21 CFR Part 11 compliant, our quality and data systems have been audited successfully by independent consultants and global pharmaceutical companies. CogState ClinicalTrials incorporates DataPoint® - a unique online tool, which allows immediate upload of data from study sites to CogState, meaning cognitive data is available for review online on the same day as testing. Ongoing data discrepancy management means that clean data-sets can be sent back to you at any number of interim points, and on the same day as last subject, last visit, enabling you to make faster decisions.

Indications:

CogState testing has been proven effective at detecting cognitive change in many specific indications and applications. These include (but are not limited to):